Pyrimidine Synthesis: Synthesis of pyrimidine derivatives

Pyrimidine Synthesis Pathway: Synthesis of pyrimidine derivatives

The pyrimidine synthesis is a similar process than that of Purines(Purines Synthesis). In the de novo synthesis of Pyrimidines, the ring is synthesized first and then it is attached to a ribose-phosphate... Read more »
Pyrimidine synthesis pathway

Pyrimidine Catabolism : UMP and CMP degradation Pathway

Animal cells degrade pyrimidine nucleotides (Pyrimidine Catabolism Pathway) to their component bases. These reactions, like those of purine nucleotides, occur through Dephosphorylation, Deamination and Glycosidic bond cleavages. After Pyrimidine biosynthesis, the newly... Read more »

Purine Catabolism and its Uric Acid formation

Purine catabolism pathway is one of the Nucleic acid Metabolism. Because nucleic acids are ubiquitous in cellular material, significant amounts are ingested in the diet. Nucleic acids are degraded in the digestive... Read more »
purine synthesis

Purine Synthesis : Synthesis of Purine RiboNucleotides

In 1948 “John Buchanor” obtains the first clues as to how this process occurs. Denovo by feeding a variety of isotopically labeled compounds to pigeons and chemically determining the position of the... Read more »