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Why Peptide bonds are Backbone of the Proteins

“The peptide is formed between the amino group (-NH2) of the first amino acid and Carboxyl group (-COOH) of the second amino acid by eliminating one molecule of water.” The amino acids are held together in a protein by covalent peptide bonds or linkages. These bonds are rather strong and serve as the cementing material […]

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Hemoglobin: Structure, Function and its Properties

Marcello Malpighi described the RBCs in 1665. Felix Hope Seyler in 1862 isolated pure Hemoglobin. Christian Bohr in 1904 discovered that hemoglobin is the transporter of oxygen. In 1912 Kutster established the structure of hemoglobin. Hans Fischer synthesized heme in laboratory in 1920 (Nobel prize, 1930). In 1945, Linus Pauling (Nobel prize, 1954) described abnormal […]

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Protein Folding is Made Easy at Cellular Level

Protein folding has nothing to do with laundry. It is, in fact, one of the central questions in biochemistry. Protein folding is the continual and universal process whereby the long, coiled strings of amino acids that make up proteins in all living things fold into more complex three-dimensional structures. By understanding how proteins fold, and […]

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Why Proteins are Very Important? How to Explain?

Proteins are very important in biological systems as control and structural elements. Control functions of proteins are carried out by enzymes and proteinaceous hormones. Enzymes are chemicals that act as organic catalysts (a catalyst is a chemical that promotes but is not changed by a chemical reaction). What are Proteins? The building block of any […]

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