Category Archives for "Lipids Metabolism"

Lipid Metabolism is the study of catabolism and anabolism of Lipids, which is occur in living organisms. This category include the metabolism of Fatty acids, cholesterol and some other molecules. We are updating more in coming days.

How Eicosanoids are synthesizing in Human body

In biochemistry, eicosanoids (preferred IUPAC name icosanoids) are signaling molecules made by oxidation of 20-carbon fatty acids. They exert complex control over many bodily systems such as In growth during and after physical activity, Inflammation or immunity after the intake of toxic compounds and pathogens, and act as messengers in the central nervous system. The […]

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Fatty Acid Synthesis: Activation, Steps and Control

Fatty acid synthesis occurs similarly to Beta-oxidation – acetyl groups are added to a growing chain, but the mechanism of the pathway is distinctly different from being simply the reverse of Beta-oxidation. Fatty acid synthesis occurs in the cytosol (not mitochondria). It uses a moiety called Acyl-carrier protein (ACP) instead of CoA and the reducing […]

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Biosynthesis of Saturated Fatty acids Notes

Glucose entering the TCA cycle is used for the biosynthesis of saturated fatty acids by converting TCA Cycle citrate to acetyl coenzyme~A (acetyl~CoA), and then malonyl~CoA, which is used to produce palmitate. The glycerol backbone of TGs comes from glycolytic glycerol-3-phosphate. Triglycerides are the primary lipid synthesized, and serve as a starting point for other […]

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What is the basic mechanism of Glycerophospholipids biosynthesis?

The most abundant phospholipids are made from glycerol. Phospholipids are important components of membranes and help transport triacylglycerols and cholesterol in the body. Typically, they have saturated fatty acids at carbon #1 (more than 90%) and unsaturated fatty acids at carbon #2 (more than 90%). There are a few differences in the lipids (and metabolic […]

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