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Category Archives for "Intermediary Metabolism"

What are the Fate of Pyruvate Molecules after Glycolysis?

Glycolysis is taking place in Cytoplasm. So Pyruvate is generated in Cytoplasm. This is to be transported into mitochondria by a Pyruvate transporter. It is a simport, where the hydrogen ion is a transporter. Here two different enzymes are involved based on the condition. They are Pyruvate dehydrogenase and Lactate dehydrogenase enzymes. There are 2 […]

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  • Updated April 12, 2019

What is Gluconeogenesis? What are the Steps and Importance in Metabolism?

Gluconeogenesis is the process of synthesizing glucose from non-carbohydrate sources. The process takes place mainly in the liver and limited extent in the kidney and small intestine under some conditions. It is also called “Endogenous glucose Production” (EGP). It is one of the metabolic pathways. The production of glucose from other carbon skeletons is necessary since […]

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  • Updated April 12, 2019

Antioxidants and their protective role against free radicals

Survey of literature indicates that each of the 60 trillion cells in the human body takes 10,000 oxidative hits/sec due to the production of harmful molecules called free radicals. Free radicals are chemically active atoms (groups of atoms) or molecular fragments that have a charge due to an excess or a deficient number of electrons. […]

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  • Updated April 18, 2019

What is Hexose MonoPhosphate Shunt and its Significance? (HMP Shunt)

The Hexose Monophosphate Shunt is also known as “Pentose Phosphate Pathway” (PPP). This is an alternative Glucose oxidation pathway. The hexose monophosphate pathway is used for the production of NADPH from NADP. The NADPH is required for biosynthetic reactions such as fatty acid synthesis, cholesterol synthesis, drug reduction, and as a  cofactor for some non-synthetic enzymatic reactions. Hexose Monophosphate shunt […]

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  • Updated April 12, 2019

Basic Overview of Carbohydrate Metabolism

Carbohydrate metabolism denotes the various biochemical processes responsible for the formation, breakdown and interconversion of carbohydrates in living organisms. The most important carbohydrate is glucose, a simple sugar (monosaccharide) that is metabolized by nearly all known organisms. Since all digestible forms of carbohydrates are eventually transformed into glucose, it is important to consider how glucose […]

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  • Updated May 28, 2016

How Eicosanoids are synthesizing in Human body

In biochemistry, eicosanoids (preferred IUPAC name icosanoids) are signaling molecules made by oxidation of 20-carbon fatty acids. They exert complex control over many bodily systems such as In growth during and after physical activity, Inflammation or immunity after the intake of toxic compounds and pathogens, and act as messengers in the central nervous system. The […]

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  • Updated June 10, 2015