What is Myoglobin? What is the function of Myoglobin?

One of the most important proteins in the human body is MYOGLOBIN. Today we are discussing about Myoglobin in this post. Generally Myoglobin is found in muscle tissue, where it binds oxygen, helping to provide extra oxygen to release energy to power muscular contractions.

What is Myoglobin? What is the function of Myoglobin?Let us come to the history of Myoglobin, Myoglobin was the first protein whose structure was determined. In 1958, Max Perutz and John Kendrew determined the 3D structure of myoglobin by X-ray crystallography. In 1962 a share of the Nobel Prize for Chemistry was awarded to John C. Kendrew for work, utilizing the technique of X-ray diffraction, that permitted construction of a three-dimensional model of crystalline sperm-whale myoglobin.

Basic points of Myoglobin:

Disease:

When muscle tissue is damaged, very large concentrations of myoglobin enters the kidneys. When this happens, myoglobin is then considered highly toxic and may contribute to acute renal failure. Muscle injury is commonly associated with the release of myoglobin, and is known to be the cause of heart attacks and many other myoalgia. Studies have shown that acute mycocardial infarction can be detected with the help of the monitoring of creatine kinase and troponin by electrocardiogram.

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Khajasta Noor Ali

Differences between hemoglobin and myoglobin.

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